7 8 The higher frequency of specific comorbidities in people with OA can be partially explained by an increased vulnerability to develop other diseases because several risk factors, such as female sex, physical inactivity, obesity and lower socioeconomic status (SES), are common to many conditions. 4 5 The most frequent pattern of OA comorbidities includes cardiovascular and/or metabolic diseases 6 as well as psychological comorbidities such as depressive symptoms. More than 65% have at least one other chronic condition, which increases with age. 3Ĭoexistence of comorbidities is common among individuals with OA. 2 OA develops slowly over time, leading to pain, joint stiffness and functional limitations. 1 Approximately 25% of the population more than 45 years old have OA, without accounting for the large numbers who never seek healthcare for their problem. Osteoarthritis (OA) is one of the most common musculoskeletal disorder in older adults. In this study we were only able to capture ICD-10 codes from healthcare delivered through inpatient care and specialised outpatient visits the ATC codes included data on drugs prescribed in primary healthcare, in hospitals, by private caregivers and occupational healthcare. To determine if socioeconomic inequalities could explain differences in comorbidity between the populations, the results were adjusted for highest educational level, country of birth and marital status.
The study captures data on comorbidities and socioeconomic status from objective data sources, not self-reported data, which gives a good opportunity to adjust for socioeconomic differences.Ĭomorbidities are identified with diagnostic codes (International Classification of Diseases, 10th revision (ICD-10) codes) and prescription of drugs (Anatomical Therapeutic Chemical (ATC) codes) using three comorbidity indices: the RxRisk Index, the Elixhauser Comorbidity Index and the Charlson Comorbidity Index, and are also described as individual diseases and as disease categories. This study describes comorbidities in a nationwide osteoarthritis (OA) population in the 3 years before participation in a standardised first-line intervention for hip and knee OA, compared with matched individuals from the general population.
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